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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1B
All Species:
18.18
Human Site:
S452
Identified Species:
40
UniProt:
Q00975
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00975
NP_000709.1
2339
262496
S452
G
S
P
F
A
R
A
S
L
K
S
G
K
T
E
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
S901
G
S
P
F
A
R
A
S
L
K
S
G
K
T
E
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S446
G
T
P
L
A
R
A
S
I
K
S
A
K
V
D
Dog
Lupus familis
XP_537779
2046
229120
G312
R
R
A
G
R
A
K
G
L
G
R
L
M
R
K
Cat
Felis silvestris
Mouse
Mus musculus
O55017
2327
261463
S452
G
S
P
F
A
R
A
S
L
K
S
G
K
T
E
Rat
Rattus norvegicus
Q02294
2336
262238
S453
G
S
P
F
A
R
A
S
L
K
S
G
K
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
W361
Q
C
I
T
M
E
G
W
T
D
V
L
Y
W
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
I95
V
I
S
K
G
N
T
I
F
R
F
S
S
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
V116
W
N
I
M
D
F
F
V
V
V
T
G
F
M
T
Honey Bee
Apis mellifera
NP_001159376
1904
215872
F170
F
I
I
E
W
P
P
F
E
Y
A
V
L
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
S232
N
R
S
L
F
I
F
S
E
E
N
F
I
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
54.2
80.1
N.A.
91.9
92.1
N.A.
N.A.
38.3
N.A.
20.7
N.A.
44.7
47.6
N.A.
39.5
Protein Similarity:
100
82.3
65.5
82.2
N.A.
94.4
94.5
N.A.
N.A.
53.3
N.A.
36
N.A.
56
58.7
N.A.
52.4
P-Site Identity:
100
100
60
6.6
N.A.
100
100
N.A.
N.A.
0
N.A.
0
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
80
13.3
N.A.
100
100
N.A.
N.A.
0
N.A.
6.6
N.A.
26.6
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
46
10
46
0
0
0
10
10
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
10
% D
% Glu:
0
0
0
10
0
10
0
0
19
10
0
0
0
10
37
% E
% Phe:
10
0
0
37
10
10
19
10
10
0
10
10
10
0
0
% F
% Gly:
46
0
0
10
10
0
10
10
0
10
0
46
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
28
0
0
10
0
10
10
0
0
0
10
0
0
% I
% Lys:
0
0
0
10
0
0
10
0
0
46
0
0
46
0
10
% K
% Leu:
0
0
0
19
0
0
0
0
46
0
0
19
10
10
0
% L
% Met:
0
0
0
10
10
0
0
0
0
0
0
0
10
10
0
% M
% Asn:
10
10
0
0
0
10
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
46
0
0
10
10
0
0
0
0
0
0
0
10
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
19
0
0
10
46
0
0
0
10
10
0
0
19
10
% R
% Ser:
0
37
19
0
0
0
0
55
0
0
46
10
10
0
0
% S
% Thr:
0
10
0
10
0
0
10
0
10
0
10
0
0
37
19
% T
% Val:
10
0
0
0
0
0
0
10
10
10
10
10
0
10
10
% V
% Trp:
10
0
0
0
10
0
0
10
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _